By Jeffrey C. Hall
The sphere of genetics is swiftly evolving and new scientific breakthroughs are occuring because of advances in wisdom received from genetics study. This sequence constantly publishes vital studies of the broadest curiosity to geneticists and their colleagues in affiliated disciplines.
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Roskin, K. , Pringle, T. , Zahler, A. , and Haussler, D. (2002). The human genome browser at UCSC. Genome Res. 12, 996–1006. , Rommens, J. , Buchanan, J. , Cox, T. , and Tsui, L. C. (1989). Identification of the cystic fibrosis gene: Genetic analysis. Science 245, 1073–1080. Klein, R. , Chew, E. , Tsai, J. , Sackler, R. , Henning, A. , SanGiovanni, J. , Mane, S. , Mayne, S. , Bracken, M. , Ferris, F. , et al. (2005). Complement factor H polymorphism in age-related macular degeneration. Science 308, 385–389.
Electrokymographic tracing at 12 points on the cardiac silhouette. 5. Blood examination for hemoglobin, serum cholesterol, phospholipids, and glucose concentrations. 6. Urine analysis. 2). The number of variables, however, has increased over time and varies from one examination to the next. For example, in the first examination, data were 40 Govindaraju et al. 2. Major Classes of Phenotypic Data Collected on the Participants of the FHS Population Data categories Physical examinations Lifestyle and habits Medical history Laboratory analysis Noninvasive Endpoints Routine examinations Anthropometry, blood pressure, lungs, heart, abdomen, ABI, neurological, and cognition Smoking, alcohol, exercise, diet, and psychosocial factors Medications, hospitalization, diagnostic testing, and cancer Lipids, diabetes, kidney, novel biomarkers, and DNA ECG, echo, Holter monitor, carotid, vascular testing, PFT, brain and cardiac MRI, and computed tomography CVD, cancer, neurological, pulmonary, bone, and cause-specific mortality collected on 30 major variables.
MacDonald, M. , Koup, R. , and Landau, N. R. (1996). Homozygous defect in HIV-1 coreceptor accounts for resistance of some multiply-exposed individuals to HIV-1 infection. Cell 86, 367–377. Lohmueller, K. , Pearce, C. , Lander, E. , and Hirschhorn, J. N. (2003). Meta-analysis of genetic association studies supports a contribution of common variants to susceptibility to common disease. Nat. Genet. 33, 177–182. Lykke-Andersen, J. (2001). mRNA quality control: Marking the message for life or death.