New PDF release: Analytical Determination of Nicotine and Related Compounds

By J.W. Gorrod, P. Jacob III

This publication presents for the 1st time a unmarried finished resource of data at the analytical chemistry of nicotine and comparable alkaloids. The editors have introduced jointly scientists from academia and the tobacco to explain the state of the art of the chemistry and analytical tools for size of nicotine. either the scope and element of the publication are extraordinary. Chapters describe the heritage, pharmacology and toxicology of nicotine, the biosynthesis of nicotine and different alkaloids within the tobacco plant, the final chemistry of nicotine and the analytical methodologies which have been used to degree nicotine and comparable alkaloids in organic specimens, in tobacco and pharmaceutical items and in tobacco smoke. there's additionally a finished overview of the chemistry and toxicology of nicotine-derived nitrosamines, a tremendous category of tobacco cancer agents.

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Extra info for Analytical Determination of Nicotine and Related Compounds and their Metabolites

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Ideals, Inc, Beltsville, MD 1990. 2 Bush LP, Fannin FF, Chelvarajan RL, Burton HR. Biosynthesis and metabolism of nicotine and related alkaloids. ), Chapman & Hall, London. 1993, pp. 1-30. 3 Bush LP. Alkaloid biosynthesis. ), Blackwell Science, Oxford, UK, 1999, pp. 812-834. 4 Legg PD, Chaplin JF, Collins GB. Inheritance of percent total alkaloids in Nicotiana tabacum L. J. , 1969: 60; 213-217. 5 Legg PD, Collins GB. Inheritance of percent total alkaloid in Nicotiana tabacum L. II. Genetic effect of two loci in Burley 21 • LA Burley 21 populations.

Tob. Chem. Res. , 1994: 48; 49. 28 Rueppel ML, Rapoport H. Aberrant alkaloid biosynthesis. Formation of nicotine analogs from unnatural precursors in Nicotiana glutinosa. J. Am. Chem. , 1971: 93; 7021-7028. 29 Boswell HD, Watson AB, Walton NJ, Robins DJ. Formation of N-ethyl-Snornicotine by transformed root cultures of Nicotiana rustica. Phytochemistry, 1993: 34; 153-155. 30 Endo T, Hamaguchi N, Eriksson T, Yamada Y. Alkaloid biosynthesis in somatic hybrids of Duboisia leichhaardtii F. Muell. and Nicotiana tabacum L.

A plant oncogene as a phosphatase. Nature, 1996: 379; 499-500. 65 Estruch JJ, Chriqui D, Grossmann K, Schell J, Spena A. The plant oncogene rolC is responsible for the release of cytokinins from glucoside conjugates. , 1991: 10; 2889-2895. , Sandberg G. and Olsson O. Hormonal characterization of transgenic tobacco plants expressing the roIC gene of Agrobacterium rhizogenes TL-DNA. , 1993: 102; 363-371. 67 Lemcke K, Schmiilling, T. Gain of function assays identify non-rol genes from Agrobacterium rhizogenes TL-DNA that alter plant morphogenesis or hormone sensitivity.

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