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By Institute of Medicine, Board on Population Health and Public Health Practices, Committee on Asbestos: Selected Health Effects

Along side drafting accomplished laws pertaining to reimbursement for healthiness results on the topic of asbestos publicity (the equity in Asbestos harm Act), the Senate Committee at the Judiciary directed the Institute of drugs to gather the Committee on Asbestos: chosen healthiness results. This committee was once charged with addressing even if asbestos publicity is causally relating to opposed overall healthiness results as well as asbestosis, mesothelioma, and lung melanoma. "Asbestos: chosen Cancers" provides the committee's finished distillation of the peer-reviewed medical and clinical literature relating to organization among asbestos and colorectal, laryngeal, esophageal, pharyngeal, and abdominal cancers.

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In addition, the reference lists of previous reviews and meta-analyses of asbestos’s possible role in the etiology of the “selected cancers” were also searched to identify the primary citations COMMITTEE’S APPROACH AND METHODS USED 23 considered. Although the committee would not necessarily accept every study given weight in earlier assessments, the members wanted to be aware of all literature that had been considered. Site-specific reviews were screened for citations on digestive system cancers (Hallenbeck and Hesse 1977, Schneiderman 1974), gastrointestinal cancers (Edelman 1988, Frumkin and Berlin 1988, Goldsmith 1982, Goodman et al.

2004. Asbestos CAS No. 1332-21-4. In: 11th Report on Carcinogens. Washington, DC: National Toxicology Program. Hill A. 1965. The environment and disease: Association or causation? Proceedings of the Royal Society of Medicine 58: 295-300. Liddell F. 1997. Magic, menace, myth and malice. Annals of Occupational Hygiene 41(1): 3-12. Ross M, Nolan R. 2003. History of asbestos discovery and use and asbestos-related disease in context with the occurrence of asbestos within ophiolite complexes. Geological Society of America Special Paper 373: 447-470.

The case-control studies considered by the committee varied a great deal with respect to control for confounding. Nearly all controlled for age and sex either by virtue of original matching criteria for control selection, by statistical adjustment, or by simply reporting on men and women separately. They vary, however, in whether they controlled for smoking, alcohol use, birthplace, region, diet, obesity, physical activity, and educational status. Studies that controlled for smoking and alcohol were given greater weight for pharyngeal and laryngeal cancers.

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