Read e-book online Asthma Mechanisms and Protocols (Methods in Molecular PDF

By K. Fan Chung (Editor), Ian Adcock (Editor)

Okay. Fan Chung and Ian Adcock compile the 1st choice of laboratory equipment for learning the molecular and mobile mechanisms of bronchial asthma. major specialists describe powerful tools for acquiring cells from asthmatic airlines, interpreting gene and protein expression in those medical samples, and utilizing molecular and mobile instruments for learning cytokine expression and unlock during this disorder. There also are state of the art strategies for learning asthma-related genes and genetic polymorphisms, and for figuring out the results of bronchial asthma therapy. ordinary and cutting-edge, bronchial asthma: Mechanisms and Protocols presents all bronchial asthma researchers-whether amateur or skilled, no matter if in experimental or scientific research-with a firstclass choice of easily reproducible pharmacological, mobile, molecular, biochemical, and genetic tools for elucidating not just the mechanisms of the disorder itself, but additionally of the medicine for asthma's remedy.

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Extra resources for Asthma Mechanisms and Protocols (Methods in Molecular Medicine No 44)

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17, 326–333. 139. Kharitonov, S. , Robbins, R. , Shinebourne, E. , and Barnes, P. J. (1994) Increased nitric oxide in exhaled air of asthmatic patients. Lancet 343, 133–135. 140. Kuo, H. , and Barnes, P. J. (1992) Effect of endogenous nitric oxide on neurogenic plasma exudation in guinea-pig airways. Eur. J. Pharmacol. 221, 385–388. 141. Taylor Robinson, A. , Phillips, R. , and Liew, F. Y. (1993) Role of TH1 and TH2 cells in a rodent malaria infection. Science 260, 1931–1934. 142. Harris, J. , Samuelson, S.

Nelson, F. , Collins, J. , and Kay, A. B. (1989) Bronchial biopsies in asthma:an ultrastructural, quantiative study and correlation with hyperreactivity. Am. Rev. Respir. Dis. 140, 1745–1753. 46. Glynn, A. A. and Michaels, L. (1960) Bronchial biopsy in chronic bronchitis and asthma. Thorax 15, 142–153. 47. Dunnill, M. , Massarella, G. , and Anderson, J. A. (1969) Comparison of the quantitative anatomy of the bronchi in normal subjects, in status asthmaticus, in chronic bronchitis, and in emphysema.

1989) Human interleukin-5 (IL-5) regulates the production of eosinophils in human bone marrow cultures: comparison and interaction with IL-1, IL-3, IL-6 and GM-CSF. Blood 73, 1504–1512. Lopez, A. , Sanderson, C. , Gamble, J. , Campbell, H. , Young, I. , and Vadas, M. A. (1988) Recombinant human interleukin 5 is a selective activator of human eosinophil function. J. Exp. Med. 167, 219–224. , et al. (1988) Highly purified murine interleukin 5 (IL-5) stimulates eosinophil function and prolongs in vitro survival.

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