By Bernd U. Budelmann (auth.), David J. Lim (eds.)
Dr. Howard condominium, founding father of the home Ear Institute and condominium Ear sanatorium usually makes use of the analogy of planting a seed while touching on setting up the home Ear Institute in 1946. thankful sufferers of Dr. condo positioned forth the concept his wisdom and cutting edge abilities should be used to extend the knowledge of listening to impairment and its remedy. these early sufferers supplied the "seed cash" to start the Institute. considering the fact that that point, the expansion has been extra special from a one-man laboratory to a multidisciplinary facility boasting over a hundred seventy five scien tists, physicians, and aid employees, all devoted to the development of otologic study and schooling. Six years in the past after a half-century of outstanding luck with prosthetic and gadget study, the Institute begun cultivating a brand new box of endeavor-cell and molecular biology. Don Nielsen, then the Institute's government vp for study and medical Director, started exploring the opportunity of hair cellphone regen eration and provided his rules to the Board of Trustees. For a interval of six months, we did loads of truth discovering to evaluate what function the Institute may perhaps soak up this excit ing new field.
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Extra resources for Cell and Molecular Biology of the Ear
Since these movements stimulate enhanced discharge in the combined presence of N-acetylated sugars and proline (Watson and Hudson, 1994), it appears that anemones redouble efforts to capture wounded prey struggling to escape by discharging additional nematocysts into the prey. 4. MORPHODYNAMIC HAIR BUNDLES Anemone tentacles are covered with cellular projections that resemble hair bundle mechanoreceptors of the acousticolateralis system. Relatively small, so called, "ciliary cones" arise from supporting cell/cnidocyte complexes (Mariscal, Conklin, and Bigger, 1978), and larger, "anemone hair bundles" arise from supporting cell/sensory cell complexes (Peteya, 1975; Mire-Thibodeaux and Watson, 1994a; Watson, Mire, and Hudson, 1997).
B 152,3-29. STEREOCILIA BASED MECHANORECEPTORSOF SEA ANEMONES GLEN M. WATSON AND PATRICIA MIRE Department of Biology, University of Louisiana, Lafayette, Louisiana ABSTRACT Sea anemones are predominately sessile marine invertebrates that detect prey using a combination of receptors. Chemoreceptors detect prey derived compounds including N-acetylated sugars and amino compounds. Activated chemoreceptors tune hair bundle mechanoreceptors to frequencies and amplitudes corresponding to prey movements.
M. (1997) Mechanotransduction of hair bundles arising from multicellular complexes in anemones. Hear. Res. 113: 224-234. , and Watson, GM. (1993) Direct monitoring of intracellular calcium ions in sea anemone tentacles suggests regulation of nematocyst discharge by remote, rare epidermal cells. BioI. Bull. 185: 335-345. M. (1994a) Morphodynamic hair bundles arising from sensory cellI supporting cell complexes frequency-tune nematocyst discharge in sea anemones. 1. Exp. Zool. 268: 282-292. M. (1994b) Cyclical morphodynamics of hair bundles in sea anemones: Second messenger pathways.