Get Computer assisted optimization of cardiac resynchronization PDF

By Raz Miri

The efficacy of cardiac resynchronization treatment (CRT) via biventricular pacing (BVP) has been tested via quite a few reviews in sufferers struggling with congestive middle failure. so that it will in achieving a tenet for optimum remedy with BVP units, an automatic non-invasive procedure in response to an electrophysiological desktop version of the guts is gifted. The offered examine investigates an off-line optimization set of rules in line with diversified electrode positioning and timing delays

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If the conduction system is blocked after bundle of His where, the excitation can not propagate to the right ventricle, the RBBB is resulted. RBBB leads to a delayed excitation of the right ventricle not through the physiological conduction system [222]. Both LBBB and RBBB lead to asynchronous ventricular contraction. 3. 3 Congestive Heart Failure The traditional view that heart failure is a constellation of signs and symptoms caused by inadequate performance of the heart focuses on only one aspect of the pathophysiology involved in the syndrome [133].

With each spontaneous depolarization a new AP is generated which in turn stimulates neighboring cells to depolarize and generate their own AP. The AP of a cardiac pacemaker cell differs from the generic AP, since it does not have a true resting potential. Its electrical charge drops to a minimal negative potential, which maintains only for a short time. Afterward it rises gradually until it reaches the threshold for the sudden depolarization that is an action potential. 15. The SA node is triggered at a rate of 60 to 100 times per minute.

Since the SA is located in the right atrium, the right atrium begins to depolarize before the left atrium and stops earlier as well. 18). In healthy hearts, there is an electrical gate at the junction of the atria and the ventricles. The wave of depolarization spreads into the atria. Then electrical conduction must be directed along inter-ventricular septum through atrio-ventricular node (AV), which slows down the conduction. 2. 18. Deploarization of atria [267]: (a) After triggering SA node, the wave of depolarization propagates through both atria, causing them to contract.

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