Progress in Neurotherapeutics and Neuropsychopharmacology: by Jeffrey L. Cummings PDF

By Jeffrey L. Cummings

Released each year, volumes during this sequence supply readers with updates of contemporary medical trial effects, affects of trials on directions and evidence-based perform, advances in trial methodologies, and the evolution of biomarkers in trials. The sequence makes a speciality of trials in neurotherapeutics, together with disease-modifying and symptomatic brokers for neurological illnesses, psychopharmacological administration of neurologic and psychiatric health problems, and non-drug remedies. each one paper is authored through a pacesetter within the sector of neurotherapeutics and medical trials, and the sequence is guided by means of an editor-in-chief and editorial board with huge event in drug improvement and neuropsychopharmacology. growth in Neurotherapeutics and Neuropsychopharmacology is a necessary replace of contemporary trials in all elements of the administration of neurologic and neuropsychiatric problems, and should be a useful source for training neurologists in addition to scientific and translational neuroscientists. additionally to be had electronically http://www.journals.cambridge.org/jid_PNN.

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2003). Dementia associated with Parkinson’s disease. Lancet Neurology, 3, 229–237. , et al. (2004). Rivastigmine for the dementia associated with Parkinson’s disease. New England Journal of Medicine, 351, 29–38. , & Bodekke, H. (1991). Pharmacologic and clinicopharmacologic properties of SDZ ENA 713, a centrally selective acetylcholinesterase inhibitor. Annals of the New York Academy of Sciences, 640, 272–275. , & Malanowski, J. (1993). Brain selective inhibition of acetylcholinesterase: a novel approach to therapy for Alzheimer’s disease.

1987) at baseline and weeks 16 and 24. 15 16 Sibel Tekin and Roger Lane Analysis Patients who had at least one dose of study medication, and at least one safety evaluation post-baseline, were considered for safety analysis. The primary population for efficacy analyses was defined as the intent-to-treat with retrieved dropout (ITT–RDO) population, comprising all randomized patients who received at least one dose of study medication and had at least a baseline and post-baseline assessment for one of the primary efficacy variables.

Veach, J. (1998). A randomized trial evaluating the efficacy and safety of ENA 713 (rivastigmine tartrate), a new acetylcholinesterase inhibitor, in patients with mild to moderately severe Alzheimer’s disease. International Journal of Geriatrics Psychopharmacology, 1, 55–65. L. (1988). Intellectual impairment in Parkinson’s disease: clinical, pathologic, and biochemical correlates. Journal of Geriatric Psychiatry Neurology, 1, 24–36. , et al. (1994). The neuropsychiatric inventory: comprehensive assessment of psychopathology in dementia.

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